Rose E. Frisch Papers Open to Research

By , February 4, 2019

~This post was co-written by Faith Plazarin, processing intern, and Hanna Clutterbuck-Cook, processing assistant.

The Center for the History of Medicine is pleased to announce that the Rose E. Frisch papers, 1921-2014 (inclusive), are open to research.

Rose E. Frisch (1918-2015) was born in the Bronx in New York. She graduated with her B.A. in 1939 from Smith College, which was partly financed by the Leopold Schepp Foundation, an organization founded by the entrepreneur and philanthropist Leopold Schepp for students in need of financial assistance. Frisch graduated with her M.A. from Columbia in 1940 in Zoology, and finally her Ph.D. in Genetics from the University of Wisconsin in 1943.

Rose worked on the Manhattan Project beginning in 1943. She was a computer doing calculations under Kitty Oppenheimer. After the bomb dropped, she left Los Alamos and returned to Boston to work in academia, where Frisch shifted her research focus from animals and reproduction to women’s reproduction. Her area of specialization was the relationship between fat content and female fertility as well as the links between fat content and breast cancer.  Her subjects were usually athletes, including ballerinas, runners, and swimmers, or those with lower fat content, such as women in underdeveloped areas of the world or women who suffered from anorexia nervosa. Frisch was one of the few women in her field of reproductive medicine. She laid the groundwork for the discovery of leptin, a protein hormone involved in the processes she researched. While leptin was not discovered until 1997, in the 1960s Dr. Gordon C. Kennedy of Cambridge University conducted initial experiments relating to a lipostat in rats.  Leptin was later to be discovered and connected to the lipostat’s function. Frisch was involved in confirming the results of Dr. Kennedy’s experiments and were linked to leptin and its connections to fertility over 30 years later. Frisch spent almost her entire academic career at Harvard University, where she taught as an Associate professor of Population Sciences and a worked as a researcher of the Center for Population Studies until she was granted emerita status in 1992.

She was a fellow of the American Academy of Arts and Sciences and the John Simon Memorial Guggenheim Foundation. Most of Frisch’s body of published works consists of articles in larger books, journals, or other serial works. However, she was also the lead editor on the scientific volume Adipose Tissue and Reproduction in 1990. Frisch published outside of academia as well. She published a children’s book called Plants that Feed the World in 1966, and a book about her life’s work for a non-academic audience, called Female Fertility and the Body Fat Connection, was published in 2002.  These publications are referenced throughout the collection.

The papers in this collection consist primarily of professional records created and collected by Rose Epstein Frisch during the course of her work as a professor at Harvard’s School of Public Health in the Department of Population and Development Studies in Boston, Massachusetts.  The professional papers consist largely of research and reference materials, reprints, publications, and writings. Also included here, are some of her personal records involving her life outside of Harvard, primarily personal correspondence and photographs.

For more information about Rose Frisch, see this article from Schepp Connections Vol. 1 No. 17 2015 (p. 6).

For information regarding access to this collection, please contact the Public Services staff.

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